Queen’s research links stress and breast cancer

Research findings from a Queen’s University study have for the first time uncovered a possible biological link between severe psychological stress and an increased risk of developing breast cancer. The study, led by biochemist Christopher Mueller, found that the stress hormone hydrocortisone may repress the activity of a tumour-suppressing gene known as BRCA1 that is related to breast cancer.

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Hydrocortisone down-regulates the tumor suppressor gene BRCA1 in mammary cells: A possible molecular link between stress and breast cancer
Genes, Chromosomes and Cancer, Volume 47, Issue 4 , Pages 341 - 352

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