Women with irritable bowel syndrome unable to regulate pain effectively

UCLA researchers have found that women who suffer from irritable bowel syndrome are unable to effectively turn off a pain-modulation mechanism in the brain, causing them to be more sensitive to abdominal discomfort than women without the condition.

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Reduced Brainstem Inhibition during Anticipated Pelvic Visceral Pain Correlates with Enhanced Brain Response to the Visceral Stimulus in Women with Irritable Bowel Syndrome
J. Neurosci. 2008 28: 349-359

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